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Funding This work was funded by grants from the National Key R&D Program of China (No: 2022YFE0209700), the National Natural Science Foundation of China (No: U21A20421), Guangdong Basic and Applied Basic Research Foundation (No: 2023B1515130009), the Postdoctoral Fellowship Program of CPSF (No: GZB20240903), the China Postdoctoral Science Foundation (No: 2024M763784)

By dividing the total radiation dose into multiple small fractions for treatment, not only can the therapeutic effect on the tumor be maintained, but normal tissues are also given more time for repair and recovery, thereby reducing the risk of long-term neurotoxicity [86, 87]