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Cyclophosphamide is a commonly used agent for neutropenia induction

395 Other research has shown statins can reduce the expression of an adhesion molecule involved in platelet aggregation, inhibit steps in the clotting cascade, and increase production of nitric oxide synthase, an enzyme involved in regulating vascular function

Roles and mechanisms of the CD38/cyclic adenosine diphosphate ribose/Ca(2+) signaling pathway

One reason for this is that the application of cosmetic ingredients is much simpler than that of pharmaceuticals, which require costly clinical trials

That sustained release profile is part of what makes it useful in a clinical context