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Many neuropeptides co-exist in the same neurons, where they influence production and secretion of one another, thus exerting a neuromodulatory role [21, 23, 37]

It should be homogeneous, deep blue

Fluorescence lifetime images of 512 512 pixels (135.2 m x 135.2 m) and 2 cycles or 5 10 5 photon counts at a pixel dwell time of 16.38 s passing through a 550 49 nm bandpass filter (Semrock, F37-551, IDEX Health & Science, LLC, Rochester, NY, United States) were recorded using the handshake plugin between Zen Black imaging software (Carl Zeiss AG, Oberkochen, Germany) and SymPhoTime 64 software (PicoQuant, Berlin, Germany)

Nat Rev Cancer 2:8390

The core advantages of these joint strategies lie in achieving synergistic effects through complementary mechanisms, reducing single drug doses to minimize toxicity, and intervening in multiple pathological stages of the disease simultaneously