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And when this occurs, often it is an immune-mediated process that can be more rapidly progressive

To maintain potency, keep the reconstituted solution refrigerated and protected from light until you are ready to use it

[0012] In various embodiments, the compound is administered as the sole medical treatment

Repletion of vitamin B12 may improve response in patients resistant to antidepressants (10) , and in older adults with major depression, long-term supplementation with a combination of B12, B6, and folic acid enhanced antidepressant treatment efficacy (40)