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The conclusions for the current study are similar to those published previously, but the availability of more specific meta-analysis results have allowed improvements to the clinical sources used in the model to greater reflect best clinical practice in administering PN

The impairment of mucociliary function caused by pyocyanin-induced ROS leads to the accumulation of mucus, creating a niche for chronic microbial infection and vicious cycles of inflammation (79), particularly relevant in chronic respiratory diseases such as CF and COPD, where P