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This pioneering research has laid the foundation for reprogramming metabolomics/metabolic state 10,11

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Proinflammatory cytokines (MCP-1 and IFN-) loaded into the outer gelatin scaffold were initially released to promote proinflammatory macrophage phenotypes, whereas anti-inflammatory cytokines (IL-4 and IL-10) incorporated into the lower biphasic ferrogel could be precisely released via the deformation of inner compartment controlled by SMF to promote healing macrophage phenotypes [386]

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Reported side effects are typically mild and transient: Localized redness, itching, or irritation at the injection site