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(2019) Open trial of vitamin B12 nasal drops in adults with myalgic encephalomyelitis/chronic fatigue syndrome: comparison of responders and non-responders

Given the relationship between thyroid and immune function, our hypothesis was that both the autoimmune process and the alterations of thyroid hormone levels in AITD could be interrelated with changes in the VIP system, which, in turn, would modulate the immune response

Sequences were then further aligned using MAFFT v7.388 126 and tree files generated using FastTree v2.1.11 127 , curated to add (NCBI) taxonomy IDs, converted to Newick format and uploaded for display using iTOL 128

These results indicate a blockage in the pathway of GSH synthesis and therefore could explain the build-up of oxidative stress that has been observed upon the combination treatment in vitro