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10.1016/j.neuro.2020.07.003 188 XuY.XiaoG.LiuL.LangM

Standard cycling protocols (4-8 weeks on, 2-4 weeks off) further minimize any theoretical dependence risk

The DNA-binding domain of the androgen receptor shares sequence areas with progesterone, mineralocorticoids, and glucocorticoids, but is most analogous to the progesterone receptor

Results: ASO induced PKM splice switching and inhibited the growth of cultured HCC cells, and increased pyruvate-kinase activity and altered glucose metabolism