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2002-2016: For nearly 15 years, Wells Fargo employees opened fake accounts for customers without their knowledge, in order to inflate sales numbers

Together, these processes trigger mitochondrial dysfunction, oxidative stress imbalance, and synaptic loss in neuronal cells, ultimately resulting in cognitive decline

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These changes could directly or indirectly lead to structural morphology changes in VCI [79, 80]

The FDA also requires that the NDA (New Drug Application) have a section demonstrating that potential consumers can understand the information included in the label and can use the medication appropriately without a doctors instructions (this is referred to as label comprehension)