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In some embodiments encompassed by the present invention, the change in biomarker amount and/or activity measurement from the predetermined level is about 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.5, 2.0, 2.5, 3.0, 3.5, 4.0, 4.5, or 5.0 times or more or any range therebetween (inclusive)

Specifically, the system consisted of a Thermo Q-Exactive in line with an electrospray source and an Ultimate3000 series HPLC consisting of a binary pump, degasser and auto-sampler outfitted with an Xbridge Amide column (Waters) (dimensions: 3.0 100 mm and a 3.5-m particle size)

Many patients experience improved digestion and reduced flare-ups

Feins, S., Kong, W., Williams, E

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