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PounsfordJ.BirchM.SaundersK.1985Effect of bronchodilators on the cough response to inhaled citric acid in normal and asthmatic subjects.662667 87

Henry, Mark R

Smoking further causes the mouth to develop bacterial colonies that accelerate the development of gum disease and slow tissue healing

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The main features of COPD are airway inflammation, remodelling and mucus retention (Vogelmeier et al., 2017), leading to limited airflow into the lungs, accompanied by wheezing, cough, difficulty in breathing, sputum production, dyspnoea, increased chest wall diameter and progressive and irreversible airway hyperresponsiveness