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Pathophysiological mechanisms of diabetic cardiomyopathy and the therapeutic potential of epigallocatechin-3-gallate

USA 88 , 1012410128 (1991)

[] Sarcopenia affects about one-third of patients with cirrhosis and up to 50% of patients with ALD or Child-Pugh class C cirrhosis, in addition, sarcopenia is independently associated with an ~2-fold higher risk of mortality in patients with cirrhosis

developed tolcapone-loaded PLGA nanosystem to reduce the hepatotoxic effect of entacapone while retaining its therapeutic efficacy in PD as illustrated in Fig