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platensis treatment (10 g-kg-1 BW for 4 days), Wistar rats (n = 9) were used in a separate study using the same protocol as described above

This pattern of hypoxemia, hypercapnia, and reoxygenation mimics an ischemia-reperfusion injury, leading to significant oxidative stress and inflammatory responses that have been strongly linked to accelerated biological aging and increased risk of neurodegenerative disease (Li and Wang, 2021)

Finally, we performed preliminary validation of the lncRNAs in the model in both normal and tumor cell lines

Importantly, the potential for intercellular transport of large structures has been previously demonstrated for mitochondria and ribosomes 88,89,90,91

In a vicious circle, feeding itself, SARS-CoV-2 may aggravate the evolution of atherosclerosis as a result of excessive and aberrant plasmatic concentration of cytokines (Vinciguerra et al., 2020