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To this end, mdivi-1, an inhibitor of the mitochondrial fission GTPase Drp1, has been used to inhibit mitochondrial fragmentation in an -synuclein rat model of PD, reducing neurodegeneration, -synuclein aggregation, mitochondrial dysfunction and oxidative stress (Bido et al., Mitochondrial motility issues are also common in PD (Smith and Gallo, 2018)

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IScience 2023, 26: 106923

Some people may see subtle improvements after a few sessions, while others might require a longer series of treatments

[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Veech RL, Bradshaw PC, Clarke K, Curtis W, Pawlosky R, King MT