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Liver 13 C-serine labeling was similar between mice fed a HF-CTRL and HF-SAAR diet

The changes in the activities of glutamine synthase and xanthine oxidase led to the overproduction of ROS, which in turn caused oxidative DNA damage and activated the p53 signaling pathway to induce apoptosis (Wang et al., 2021a)

Interestingly, preconception administration of liraglutide 1.2 mg and metformin was associated with increased pregnancy rate per embryo transfer and cumulative pregnancy rate in women with obesity in PCOS compared to metformin monotherapy, despite similar weight reduction 98

Nrf2 activator molecules with an ,-unsaturated carbonyl group exhibit strong anti-inflammatory and antioxidant properties

2013;8(3):e49976