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Description

The major prostaglandins are distinguished by the substituents on the cyclopentane ring: PGE2 (a 9-keto, 11,15-dihydroxy structure) mediates inflammation, pain sensitization, and fever through EP receptors

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In: Immunology and rheumatology in questions

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Charytoniuk T, Zywno H, Berk K, Bzdega W, Kolakowski A, Chabowski A, Konstantynowicz-Nowicka K

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In terms of mechanisms, covalent inhibitors and allosteric modulators, through irreversible binding or regulation of allosteric sites, hold promise for achieving more durable and specific targeted inhibition [263]

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