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Mature HDL can acquire addition cholesterol from cells via ABCG1, SR-B1, or passive diffusion

doi: 10.1111/j.1365-3040.2009.01926.x

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Winter et al., 2015)

We showed that this genetic manipulation led to the formation of tumor-like overgrowths with many hallmarks of human CRC such as increased proliferation, a block in cell differentiation and cell polarity, and disrupted organ architecture 16