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Fetal bovine serum (FBS) was purchased from Cell Clone Inc

5.2 CUL5 mediates the specific degradation of aberrant translation products Okumura et al

coli metabolite database (ecocyc.org) for the most abundant digitate colony peaks (Table S1) (Keseler et al ., 2017)

However, the poor fidelity to the in vivo conditions limits its efficacy, widening the translational gap between preclinical studies and clinical trials ( Hydrogel-based cell culture systems, spheroids and organoids, or their combination currently represent valid 3D cell culture models ( e.g

Despite limitations related to the clinical heterogeneity of the studies, particularly regarding the type of maintenance, the authors concluded that there was no significant difference in OS between the strategies