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7 , eabf8711 (2021)

Similar findings were reported in prospective clinical studies.68,69 A large multicenter RCT (n=194), however, found no significant differences with placebo.70 A meta-analysis of the above findings for a total of 480 patients showed a favorable effect on facial appearance.70 Multiple oral antioxidants and anti-inflammatory agents, such as vitamins A, C, D, and E, green tea polyphenols, niacinamide, and trace elements such as zinc may help mitigate signs of skin aging

Areas of concern are that its supplements can provide very high amounts of specific nutrients, and that it does not publish its supplements test results online, meaning customers cannot check the content, purity, and safety of the products they buy.

Hepatol Res 2008;38 Suppl 1:S3-8

Restor Neurol Neurosci 28:589603 Das S, Bonaguidi M, Muro K, Kessler JA (2008) Generation of embryonic stem cells: limitations of and alternatives to inner cell mass harvest