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The recruitment of TAMS, myeloid derived suppressor cells (MDSCs), regulatory T-cells, and regulatory T-cells all of which inhibit antitumour immunity contributes to this proneoplastic environment

290,291 Another proposed mechanism is that mTOR regulates the crosstalk between mitochondria and the nucleus, stabilizing the key protein Clk-1, which is essential for mitochondrial signaling communication

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