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Among the 12 TMs of hTauT, TM1-TM5 and TM6-TM10, two structurally similar but topologically inverted repeats (IRs), form the transporter core (Fig

Oxidative damage is implicated as a pertinent factor involved in its pathogenesis

Moreover, including biosensors into these organ-on-chip systems facilitates real-time monitoring of essential parameters, including pH and reactive oxygen species (ROS), thereby confirming the activation of microenvironment-responsive linkers in the context of an infection