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Role of lysyl oxidase in myocardial fibrosis: from basic science to clinical aspects

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Relief becomes more noticeable as the proliferative phase advances

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The recognition sequence is cleaved C-terminally after Asn allowing a traceless release of the attached payload if the cargo is conjugated to the C-terminus, while the N-terminus of the linker is coupled to the carrier (Stern et al., 2009

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For both, topical class II steroids are considered first-line for those with mild disease inadequately controlled with non-pharmacologic interventions

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Avoid repeated freeze-thaw cycles, which may degrade the formulation and reduce its biological activity

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