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For example, studies have shown that the active compounds in the Chinese medicine Yueju exert antidepressant effects by upregulating the expression of pituitary adenylate cyclase-activating polypeptide (PACAP) in the hippocampus [532]

Stack 3: metabolic neuropathy support (BPC-157 + SS-31 or MOTS-c) For neuropathies with a strong metabolic component, particularly diabetic peripheral neuropathy, combining a direct nerve repair peptide with a mitochondrial support peptide addresses both the damage and its upstream metabolic cause