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In glioma, results of phase I trial NCT02454634 recently published in Nature (202) showed that topical Imiquimod combined with IDH1 peptide vaccine induced 93.3% immune responses in IDH1R132H-mutated patients while adverse effects are within grade I

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To define a CDK11-dependent rate-limiting step in spliceosome activation, we decided to determine the precise protein composition of spliceosomes blocked by OTS964 in cells

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