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Description

"Hybridization" refers to a reaction in which one or more polynucleotides react to form a complex that is stabilized via hydrogen bonding between the bases of the nucleotide residues

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the chemical synthesis uses automated, solid-phase oligonucleotide synthesis machines with 2-acetoxyethyl orthoester (2-ACE) (Scaringe et ah, J

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doi:10.1152/ajpendo.00201.2006 Sackmann-Sala L, Ding J, Frohman LA, Kopchick JJ

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Gradual dose escalation minimizes gastrointestinal side effects such as nausea [4] [6]

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