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The immune-related pathways are the top GO biological process gene sets enriched in genes downregulated in double knockdown compared to mrps-5 RNAi (Fig

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Combined with the high cost of treatment, it results in a substantial socioeconomic burden ( The discovery of tumor necrosis factor (TNF-) as a crucial cytokine in the pathogenesis of ARDs as rheumatoid arthritis (RA) led to the development of the first group of biologic drugs: TNF- inhibitor ( Great progress has been made in cell therapy particularly due to the development of genetically modified receptors, such as chimeric antigen receptors (CARs) in T cells (CAR-T)

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Sorensen, S.B., Bech, L./ M., Muldbjerg, M., Beenfeldt, T