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Peer review Peer review information Nature Immunology thanks Felipe Andrade, Andras Perl, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion

Acknowledgements This paper is in memory of Professor Adrienne Gordon, the original AG, who advised us on this project and many past ones

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