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PMID: 14648529

In this study we investigated transcriptomic landscape of GH-producing PitNETs on several levels and functional modelstumour tissue of patients with and without SSA preoperative treatment, tumour derived pituispheres and GH3 cell line incubated with SSA to study effect of medication on gene expression

The cells from each well were harvested on a glass fiber filter (Perkin-Elmer, Rodgau-Jgesheim, Germany), washed, and dried

Recently, Metha et al[84] reported that choline and -lipoic acid treatment reduces ROS production and isoprostanes in BAL fluid and thus suppresses oxidative stress

The enzymatic activity of the three NOSs requires the presence of flavins FMN and FAD, tetrahydrobiopterin (H 4 B), calmodulin (CaM), zinc ion (Zn), NADPH, L-arginine (L-Arg) and molecular oxygen (O 2 ) [27] (Table 1a)