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Therefore, preparing animal feeds from credited sources, improving of the storage condition of livestock inputs (137), improving the quality and accuracy of AFs detection systems (138), improving of animal feed manufacturing procedures (139), and regular monitoring of animal feeds to identify the source of AFs contaminants are possible strategies to reduce the concentration of AF pollutants in dairy products

Immunol., 07 June 2019, doi:10.3389/fimmu.2019.01296)

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Summary Accordingly, a first object of the disclosure relates to an antibody-drug conjugate (ADC) of the formula (I): Ab-[L-D]p (I), wherein : Ab is an anti-folate receptor alpha (FRa) antibody which binds specifically to SEQ ID NO:12, L is a cleavable linker moiety bonded to said anti-folate receptor alpha (FRa) antibody preferably via a thiol residue, D is a cytotoxic drug moiety bonded to L, p is from 1 to 8, preferably from 6 to 8, and more preferably p is 8

The mitogen-activated protein kinase (MAPK), phosphatidylinositol 3-kinase (PI3K) and Rho-like GTPase contribute to non-canonical pathway of TGF- (Figure 2) (Derynck and Zhang, 2003