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We hypothesize that the specific tumor cell killing effect of melatonin compensates for the protective effect of ferroptosis inhibition on tumor cells, thereby simultaneously achieving enhanced radiosensitivity and reduced radiation-induced injury

Dozens of studies on conditions like diabetic neuropathy and metabolic dysfunction point to this as a common and effective amount

this action not only disrupts intercellular junctions but also induces the degradation of basement membrane components, including laminin and collagen IV, further damaging the BBB (64)

Growth was monitored for 72 h with OD 600 values measured every 24 h

Furthermore, HTY has been associated with increased angiogenesis-related responses, which is important for wound healing because new blood vessel formation supports oxygen and nutrient delivery to damaged tissues [103, 107]