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Description

RELN encodes Reelin, a glycoprotein that plays an important role in synaptic function and is a ligand for lipoprotein receptors such as very low-density lipoprotein receptor (VLDLR) and apolipoprotein E receptor 2 (ApoER2

This method requires a polynucleotide which codes for a polypeptide of the invention that operatively linked to a promoter and any other genetic elements necessary for the expression of the polypeptide by the target tissue