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Abstract Glutathione (GSH) has a crucial role in cellular signaling and antioxidant defenses either by reacting directly with reactive oxygen or nitrogen species or by acting as an essential cofactor for GSH S -transferases and glutathione peroxidases

However, the synthesis of Bi-based CAs presents significant challenges, such as elevated temperatures, an oxygen-free atmosphere, and the use of toxic organic solvents [48, 49]

Ceruloplasmin is a copper-containing protein synthesized by the liver

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The PSPen is designed for repeated use, and repeated injections at the same site can cause subcutaneous tissue changes that affect absorption