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Short-chain acyl-coenzyme A dehydrogenase deficiency (SCAD): The SCAD enzyme is an intra-mitochondrial enzyme of beta oxidation that catalyzes the oxidation of C4-C6 carbon acyl-CoA fatty acid esters to produce 2 trans-enoyl-CoA fatty acid esters

Obesity is significantly positively correlated with various abnormalities in liver function indicators, such as the serum enzyme indicators ALT, AST, and AKP, which are significantly increased [31]

Preliminary evidence for the reliability and validity of an abbreviated profile of mood states

The hyper-inflammatory response caused by SARS-CoV-2 induces the process of immunosenescence, increases endothelial cell damage, and leads to myofibrillar degradation and muscle wasting (sarcopenia) due to mitochondrial dysfunction and autophagy [102]

Interestingly, five of our participants with Qualifying variants in peripheral neuropathy-related genes have substantial peripheral pain, consistent with CMT (Table 5)