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Abstract Highly active antiretroviral therapy (HAART) has significantly increased life expectancy of the human immunodeficiency virus (HIV)-positive population

And our previous microarray data did find the decrease of GPX3 in the aged prostate

Furthermore, a clinical trial involving 39 healthy adults who consumed roselle beverages rich in polyphenols and PCs reported significant increases in the serum levels of SOD and GSH-Px and reduced GSH-Rd, following the daily intake of 200 mL of the beverages (containing 3.92 g of gallic acid and 3.3 g anthocyanins of cyanidin-3-glucoside) for six months

Increased extracellular GSH (eGSH) suggests active transport by ATP-binding cassette transporters, including MRP1/ABCC1