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Herein we discuss the relevant and contemporary pathomechanisms of CIPN, along with several potential biomarker candidates for CIPN and its future directions to translate it into routine clinical practice

The implications of TMAO for patients with ESRD are not limited to its direct influence on renal function

These changes include intestinal conduction and consumed protein absorption, reduced dietary fiber intake, oral iron treatment, and heavy use of antibiotics ( Combustibility and uremic toxins play a leading role in the pathophysiology of atherosclerosis and other complications involved in CKD ( 9.9 Kidney Crosstalk and Inflammation in the Intestine Due to CKD Development Kidney crosstalk in the intestine, which is affected by the intestinal microbiota in most cases, plays an integral role in CKD development (Tanida et al., 2005

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Noticeably, CAFs used in our reporter assay express low amounts of AR, as compared to those observed after overexpression of hAR (Fig