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99% Purity HPLC & Mass Spectrometry Verified Batch-Specific Certificate of Analysis (CoA) Included Sterile Lyophilised Powder | GMP Manufactured Fast Dispatch to Ireland | Peptides Ireland Stock Ipamorelin , Aib-His-D-2-Nal-D-Phe-Lys-NH2 , is a synthetic pentapeptide growth hormone secretagogue developed at Novo Nordisk through a systematic structure-activity relationship programme directed at identifying GHS-R1a agonists with selective GH-releasing activity free from the prolactin and cortisol co-secretion that characterised first-generation hexapeptide GH secretagogues including GHRP-6 and GHRP-2

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GHRP-2 reliably elevates plasma ACTH and cortisol in both rodent models and the early human pharmacology studies from the 1990s

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Ipamorelin has been studied extensively in preclinical research for its selective GHS-R1a agonist activity and effects on growth hormone secretion pathways