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doi: 10.4049/jimmunol.2100752 21 Van den BosscheJBaardmanJOttoNAvan der VeldenSNeeleAEvan den BergSMet al

Ginseng may exacerbate insomnia in some people, even though it helps to alleviate insomnia in others

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If a significant part of this mechanism relies on re-absorption from bile that would be an issue due to lack of intrinsic factor breaking the "enterohepatic recirculation"