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Cagnin, Gerhard, and Banati [79] briefly outline the rationale for employing PET for imaging of activated microglia to detect in vivo inflammatory changes occurring in a variety of brain diseases and at different disease stages, and to monitor the progression of neuroinflammation as an in vivo marker of disease activity

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The peptide works through multiple mechanisms including enhanced angiogenesis (blood vessel formation), increased collagen synthesis, and activation of growth hormone receptors on fibroblasts

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