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This metabolic adaptation is orchestrated by regulators such as the serine/threonine protein kinase PknG, which remodels the bacterial proteome in response to hypoxia and alters nitrogen metabolism (Lima et al., 2021)

The reaction was stopped by washing the cells in Dulbeccos Modified Eagles Media/Hams Nutrient Mixture F12 (DMEM/F12) (Sigma-Aldrich

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Under pathological conditions, excessive lactate accumulation promotes aberrant lactylation patterns that may drive persistent inflammation, metabolic reprogramming, and neuronal dysfunction by reshaping chromatin accessibility and transcriptional landscapes