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Immunohistochemical studies have demonstrated reduced expression of UGT throughout the hepatic lobule in individuals with GS compared to normal controls

Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy

N-(2-Chlor-6-methylphenyl)-2-[[[[2-(2-pyridinyl)ethyl]amino]carbonyl]amino]-6-benzothiazolcarboxamid

Another approach to generate transgenic AIH animal models is the expression of antigens under the control of liver-specific promoters: since this approach is not capable of inducing liver damage on its own in the liver, a tolerogenic organ, it has to be coupled with adjuvants and/or adoptive transfer of antigen-specific T cells

To maintain a healthy barrier the epithelial cells are constantly in a balance of proliferation, migration, and differentiation, migrating from the base of the crypts to the crypt surface or villous tip