g , Mitochondrial abundance of GSSG in HEK-293T SLC25A39 knockout cells transduced with the indicated cDNAs
doi: 10.1016/j.heliyon.2024.e38791 7 rskldE.Lohmeier-VogelE.CaoR.RoosS.RdstrmP.Van NielE
Abstract Background The aim of this study is to explore the effects of TGF-1 on autophagy and apoptosis induced by exogenous hydrogen peroxide (H 2 O 2 ) in annulus fibrosus (AF) cells and possible signal pathways involved in this process
Introduction Glioma is a threatening primary malignancy tumor in the central nervous system ( Recently, immunotherapy represented by PD-1/PD-L1 and CTLA-4 has shown excellent clinical effects on numerous tumors such as melanoma and non-small cell lung cancer ( The glioma immune microenvironment is composed of glioma cells, immune cells, cytokines and so on ( Ferroptosis is a form of regulated cell death driven by lipid peroxidation, a consequence of imbalance between cell metabolism and redox homeostasis ( Overview of Ferroptosis and Potential Singling Pathway in Glioma The main characteristics of ferroptosis include: cell morphology (mitochondria crista, volume reduction, and increase of membrane density)
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