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When specifically released into tumor cells, GOx catalyzes the oxidation of glucose in tumor cells and blocks the energy supply to tumor cells

J Clin Invest 131(22):e152067 Zhang P et al (2021a) ATG7-dependent and independent autophagy determine the type of treatment in lung cancer

The first reaction is catalyzed by -glutamylcysteine synthetase, joining L-glutamate and L-cysteine into -glutamylcysteine

Additional information Publisher's note: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations