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The presence of anti-GFAP antibodies in serum and cerebrospinal fluid is a critical diagnostic criterion, as clinical manifestations are nonspecific and can include movement disturbances, paresthesia, visual impairment, brainstem syndrome and autonomic dysfunction 259,260,261,262

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10.1097/phm.0000000000001345 80 YonemitsuR.TokunagaT.ShukunamiC.IdeoK.ArimuraH.KarasugiT.et al (2019)

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307 Technological advancements, such as wearable sensors and biofeedback devices, play a pivotal role in integrated approaches