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Nutrigenomic interactions involving genes such as APOE, MTHFR, SIRT1, and Nrf2 have been implicated in modulating oxidative stress responses, lipid metabolism, and neuroinflammatory pathways

Front Pediatr

Sly LM, McKay DM

Effects of two-year Vitamin B (12) and folic acid supplementation on depressive symptoms and quality of life in older adults with elevated homocysteine concentrations: additional results from the B-PROOF study, an RCT