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Overall survival was 2-4 months for patients with unresected hepatic metastases versus 28 months for those with completly resected liver metastases.[78] A recent metaanalysis of five studies also revealed a significant improvment in overall survival after surgery compared to non-surgical procedures.[109] The majority of noncomparative studies also reported benefit from resection of metastases.[66,75,110-114] All studies observed that R0 resection was associated with longer overall survival than R1 or R2 surgery.[75-78] The outcome of surgery is also influenced by the number of metastases, length of disease-free interval and limited disease distribution.[78,115,116] However, eligibility for surgery upon the extent of disease and the number of metastases varied in the studies