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And sometimes they can be blinded by a goal. Of course, as we now know, this was no small breakdown

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doi: 10.1002/mnfr.200500003 157 DelmasDJanninBLatruffeN

All study participants were randomly assigned to an experimental treatment group that received subcutaneous injection of cagrilintide, once-weekly, in doses of either 0.3, 0.6, 1.2, 2.4, or 4.5 mg, as well as a one-daily 3.0 mg dose of liraglutide, and a volume matched placebo for control purposes

What Phase 2 is not powered to do is detect rarer adverse events, confirm long-term safety, or establish outcomes over years of use