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ANR-REPHARE 19CE120027 and ANR-RoxRNase 20-CE12-0025)

Metabolic regulation of the Th17/Treg balance in inflammatory bowel disease

For example, programmed death ligand-1 (PD-L1) blockade therapy and CD8+ T cells increase ROS levels by releasing interferon gamma (IFN) which promotes the binding of transcription factor STAT1 to the SLC7A11 transcriptional start site, downregulating expression