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First, Sensing and Destruction: COFs, equipped with precisely integrated sensitizing units, efficiently respond to external stimuli (e.g., light, ultrasound, radiation) or endogenous triggers (e.g., H 2 O 2 ), generating intense local biochemical effects such as bursts of ROS, hyperthermia, or DNA damage ( Figure 2 ) (155, 156, 166)

Apigenin (20 mg/kg) was also able to prevent the reduction in blood pressure and scratching behavior caused by anaphylaxis induced by antigen and Compound 48/80, however did not significantly affect blood flow [133]

Zhao J, Ouyang Y, Wang H, Lai H, Hu S, Tang L, et al

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