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Description

The limited in vitro lifetime of human diploid cell strains

WHO Library Cataloguing-in-Publication Data

AMDH-1 is the third enzyme in the catabolism of histidine to glutamate

Collectively, a dysregulated MGBA can promote neurodegeneration via multiple converging mechanisms: chronic peripheral and central inflammation, impaired barrier and metabolic support for the brain, accelerated protein misfolding, and diminished neuroprotective signaling