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Experimental data indicate that APS intervention significantly enhances cardiac function indices in rat models of radiation-induced heart disease (RIHD), mitigates pathological damage to myocardial tissue, and reduces serum levels of inflammatory factors

The intermediate form of the enzyme is further reduced by the formation of an intra-molecular disulfide bond between the two active site cysteines, leaving the enzyme in an oxidized form, from which the vicinal thiols are regenerated by the FAD(H)-intermediated hydride transfer from NAD(P)H

PMID: 35396206

Two Caucasian participants had a total of 3 AEs (headache, presyncope and dysmenorrhoea)